Week 8 Assignment 1: Short Answer Assessment2 Question 1. In 3 or 4 sentences, explain the appropriate drug therapy for a patient who presents with MDD and a history of alcohol abuse. Which drugs are contraindicated, if any, and why?

Be specific. What is the timeframe that the patient should see resolution of symptoms? For the treatment of these co-occurring disorders, antidepressant and alcohol use disorder (AUD) drug combinations such as sertraline with naltrexone and acamprosate with escitalopram have shown some promise, with beneficial results for both AUD and depressed symptoms (McHugh & Weiss, 2019).According to studies, combining naltrexone, an opioid antagonist, with sertraline, an SSRI, can enhance mood and increase the likelihood that an alcoholic will abstain from drinking for a longer period of time (DeVido & Weiss, 2012).Bupropion should be avoided as an antidepressant since it increases the risk of seizures in people with a history of alcohol use disorder (PDR.net, n.d.).Typically, it takes anywhere between two and six weeks of taking an antidepressant to start feeling better (Harvard Health Publishing, 2018).

Question 2. List 4 predictors of late onset generalized anxiety disorder. The principal predictors of late-onset incident GAD, as outlined by Zhang et al., (